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Non-Steroidal Anti-Inflammatory Drugs
Canadian Study of Health and Aging
Average Follow-up Time Detail
We estimated the total person-years of follow-up by multiplying the reported average follow-up time by the number of persons.
Use of supplements of vitamins C and E was measured at baseline either using a structured interview during clinical examination or from a self-administered questionnaire. For the structured interview, participants were asked by a nurse to list current medications and supplements. For the questionnaire, participants were asked to list all medications and supplements. Information on dose was not requested.
This table includes results for only 2 categories of vitamin use, to the exclusion of participants in other categories (e.g., vitamin E and/or C, multivitamins only). Therefore, the percents shown do not add up to 100%.
Participants were residents from five geographic regions in Canada (British Columbia, the Prairie Provinces, Ontario, Quebec and the Atlantic Provinces).
Screening and Diagnosis Detail
Modified Mini-Mental State Examination (Teng 1987)
Diagnostic and Statistical Manual III-Revised
National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)
Total Dementia Definition
: Dementia via DSM III-R.
Participants first underwent screening using the 3MS. Those who scored less than 78 and those unable to be screened underwent a clinical examination including medical history, informant interview, physical examination, neuropsychological testing, and laboratory tests.
Covariates & Analysis Detail
Cox proportional hazards regression
In Cox proportional hazards models, age was used as the time scale.
history of smoking
history of smoking