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AlzRisk Paper Detail

Reference: Mangialasche, 2010
Cohort: Kungsholmen Project
Risk Factor: Nutritional Antioxidants

Average Follow-up Time Detail
Maximum follow-up time was 6.4 years.

Exposure Detail
Fasting venous blood samples were taken at baseline stored
at −80 degrees Celsius until analysis. Plasma vitamin E was measured with reverse-phase high performance liquid chromatography (HPLC).

Ethnicity Detail
Participants were sampled from the population of the Kungsholmen district of Stockholm, Sweden. No information on the ethnic background of participants has been provided.

Screening and Diagnosis Detail
Screening Method:
DSM IIIR - dementiaDiagnostic and Statistical Manual III - Revised - dementia
MMSEMini-Mental State Examination (Folstein 1975)

AD Diagnosis:
DSM IIIR Diagnostic and Statistical Manual III-Revised
Medical History
NINCDS ADRDA National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)

Covariates & Analysis Detail
Analysis Type:
Cox proportional hazards regression

AD Covariates:
ALCalcohol intake
APOE4APOE e4 genotype
MMSEbaseline MMSE
BMIbody mass index
SVSfollow-up survival status
SMsmoking status