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AlzRisk Paper Detail

Reference: Hughs, 2009
Cohort: Kame Project
Risk Factor: Obesity

Exposure Detail
Method of BMI ascertainment: measurement by trained interviewers

"At the baseline examination, anthropometric measurements including height, weight, WC, and hip circumference were taken by trained interviewers and recorded for each participant. Only weight was measured at each of the follow-up examinations. BMI (weight[kg] over height squared [m2] was considered the primary index of body weight, since it is scaled according to height and was categorized as obese (BMI>=25), overweight (BMI=23.0-24.9), normal (BMI=18.5=22.9), and underweight (BMI <18.5) according to cutoffs proposed by the International Obesity Taskforce for Asian populations."

Screening and Diagnosis Detail
Screening Method:
CASICognitive Abilities Screening Instrument (Teng 1994)

AD Diagnosis:
CDR Clinical Dementia Rating (Berg 1988)
CERAD Consortium to Establish a Registry for Alzheimer’s Disease (Morris 1989)
DSM IV Diagnostic and Statistical Manual IV
NINCDS ADRDA National Institute of Neurological and Communicative Diseases and Stroke/Alzheimer's Disease and Related Disorders Association Criteria (McKhann 1984)

Covariates & Analysis Detail
Analysis Type:
Cox proportional hazards regression

AD Covariates:

TD Covariates: